Amantadine Hydrochloride Oral Solution, USP
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Amantadine Hydrochloride Capsules, USP
Amantadine hydrochloride is a stable white or nearly white crystalline powder, freely soluble in water and soluble in alcohol and in chloroform. Amantadine hydrochloride has pharmacological actions as both an anti-Parkinson and an antiviral drug. Each capsule intended for oral administration contains 100 mg amantadine hydrochloride and has the following inactive ingredients: black ink (Hypromel...
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Inactive Ingredients Propranolol Hydrochloride Oral Solution is available for oral administration containing either 20 mg per 5 mL or 40 mg per 5 mL of propranolol hydrochloride USP. The oral solution contains the following inactive ingredients: citric acid anhydrous, crème de menthe flavor, disodium edetate, methyl paraben, propylene glycol, propylparaben, purified water, saccharin sodium, sor...
متن کاملA double-blind cross-over trial of amantadine hydrochloride in Friedreich's ataxia.
We performed a double-blind cross-over study with amantadine hydrochloride in 12 patients with Friedreich's disease and 2 with autosomal dominant cerebellar ataxia. Patients were randomly assigned to a placebo-amantadine or amantadine-placebo sequence. The interval between the treatments was two weeks. Patients were graded according to a functional ataxia scoring scale and videotaped in basal c...
متن کاملComparative single-dose pharmacokinetics of amantadine hydrochloride and rimantadine hydrochloride in young and elderly adults.
The single-dose pharmacokinetics of amantadine hydrochloride and rimantadine hydrochloride were compared in a randomized, two-period, crossover study involving six young (less than or equal to 35 years) and six elderly (less than or equal to 60 years) adults. Subjects ingested single 200-mg oral doses after an overnight fast, and serial plasma (0 to 96 h), nasal mucus (0 to 8 h), and urine (0 t...
متن کاملSevere reversible neurological complications following amantadine treatment in three elderly patients with renal insufficiency.
reflexes in both hands. Parkinsonism symptoms, such as rigidity, were mild, but she could not stand or walk. Brain computed tomography showed no apparent ischemic changes, and electroencephalography showed no obvious paroxysmal discharges or triphasic waves. Her plasma amantadine hydrochloride level was high (4,900 ng/ml), and she was eventually diagnosed with amantadine toxicity. After cessati...
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